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January 11, 2021

Wearable 24/7 glucose monitor (nonstop, needleless) at CES 2021

Quantum Operation’s CES Exhibit to Showcase the World’s First Glucose Measuring Wristband that Enables Truly Nonstop Monitoring Health tech startup will also present a nonstop oxygen saturation (SpO2) monitoring wristband. TOKYO (Jan. 10, 2021) At CES 2021 (Jan. 11-14, online), Quantum Operation Inc., a Tokyo-based healthcare IoT startup, will present the world’s first noninvasive glucose monitor that is capable of truly continuous measurement. The company’s patented spectrum sensing technology enables the monitoring sensor to accurately measure glucose in a person’s bloodstream through the skin while being worn around their wrist. This monitor eliminates the need and pain of daily needle uses for diabetic patients. During CES, Quantum Operation will also showcase its oxygen saturation measuring sensor (SpO2) that can be worn around the wrist. The key to achieving this noninvasive 24/7 monitoring are Quantum Operation’s core technologies that include the novel spectrometer materials one of which is designed to emit an optimal spectrum, and another that is highly responsive to target spectra as well as the innovative firmware that efficiently extract targeted data by canceling noise. These technologies can be …

November 18, 2020

Listed as a participating start-up company in Saitama Sports Start-up (SSS)

Quantum Operation Inc. is listed as a participating start-up company in the 2020 Saitama Sports Start-up (SSS, sponsored by Saitama Prefecture and Saitama Industrial Development Corporation). Participating start-up companies in the 2020 Saitama Sports Start-up (SSS) http://www.pref.saitama. lg.jp/a0803/sogyo-files/sss.html Quantum Operation Inc. is working on the themes presented by Urawa Red Diamonds. We would be happy to report details of our collaboration with them as well as their progress in the future. Translated with www.DeepL.com/Translator (free version)

November 4, 2020

Published in [Health Tech Startup Feature]

Quantum Operation Inc. today announced that Healthtech/SUM2020 Health Tech Startups with Potential for Success https://www.healthtechsum.jp/startup. html This information was also published in the Nihon Keizai Shimbun on November 4, 2012. https://www.healthtechsum.jp/startup. html Now you can also vote for three promising startups. We hope you’ll join us.

Our efforts

Our efforts

1. Reducing the burden of children having to stick needles in every day

--Research and development of non-invasive blood glucose sensors--

The world’s first non-invasive blood glucose measurement sensor under research utilizes our proprietary technology to eliminate the need for invasive blood glucose measurement.

Quantum Operation supports the activities of IDDM Network Japan.

2. Patient Monitoring Technology NEMURIE

nFOPT®

24時間の自動健康管理「ネムリエ」では、nFOPT®によるモニタリングシステム「スマートケアシステム」により、呼吸数と呼吸波形、心拍数、咳、睡眠の質など、ウイルスによるさまざまな初期症状を正確かつ瞬時に追跡できます。 体動（参考データとして心拍、呼吸、咳、睡眠の質を含む）を検知することができます。
NEMURIE, a 24-hour automated health management system, can detect body movements (including heart rate, breathing, coughing and sleep quality as reference data) through the Smart Care System, a monitoring system powered by nFOPT®.

光ファイバーの優位性

圧電光ファイバー – nFOPT®
技術と安全性一呼吸毎に電磁波を
変化させ測定		Full Reflection Principal
（全反射原理）
電磁波の変化なし
体動の判定体動の判定ができない
（感度の問題により）		患者の生理活動に基づいて、
体動を始めとする状態を検知
校正時間長時間の校正と
検証時間		短い校正時間
再校正する必要なし

NEMURIE supports monitoring the status of symptoms of the new coronavirus COVID-19

  • It is presently difficult to identify the symptoms and this often leads to misdiagnosis.
  • The new coronavirus COVID-19 causes LRT (lower respiratory tract) infection, with early symptoms of cough, shortness of breath and shallow breathing.
  • The PCR test only identifies symptoms at the time of measurement and does not provide continuous confirmation of symptom changes.
  • To prevent the spread of the virus, it is necessary to identify and isolate infected people as early as possible.
  • By measuring changes in body movement and respiration, it is possible to make more meaningful estimates, and better judgements, regarding the symptoms of the new coronavirus.

Protecting Health Care Workers from the New Coronavirus

Benefits of Smart Care Systems

  • Remote monitoring : reducing the number of contacts between infected and uninfected individuals.
  • 24-hour monitoring : 24-hour real-time visibility of all patients is reducing the psychological burden on staff.
  • Abnormalities detected : Immediately detects changes in patients and sends alerts to staff.
  • Reduced medical resource use : It reduces the number of patrols, reduces the use of resources such as the use of protective clothing, and saves staff time and effort.
  • When combined with the optional oxygen monitoring watch, the system can also monitor the oxygen level in the patient's body.

使用方法1:隔離環境下での自動モニタリング

使用方法2: 複数患者への24時間自動モニタリング

Support for monitoring the status of symptoms of the new coronavirus

Coughing Tossing and turning in bed Nodding Shivering
With this function, each symptom can be detected even for patients who are unable to move.

3. Preventing Severe Pneumonia, a Drowning Affliction

--Development of wrist-watch-type SpO2 sensor / heart rate, respiration and body movement sensors--

IoT sensor detects vitals related to respiratory diseases
・Used to screen patients with sleep apnea syndrome (SAS).
・Used for prevention of interstitial pneumonia, a side effect of anticancer drugs.
・Used to prevent the spread and severity of COVID-19 infection.
*Preparing for medical device application

4. Preventing heat stroke and saving lives of working people living and working in the heat wave

-- Using IoT sensors and heat stroke prediction algorithms--

Focuses on individual vital signs and predicts heat stroke.
・A joint study with Professor Kuroki of Chiba University of Science predicts heat stroke.
・We have started PoC (Proof of Concept) at construction sites from 2020.

5. Building a community-wide care platform that doesn't make people sick

--Building Blockchain DB & SNS with Healthcare Banding--

(1) Development of local currencies

(2) Integration of Local Currency into Community Inclusive Care Platform

Building a foundation for the revitalization of the local economy through local currencies.
Using local currencies to provide incentives for community-based care systems.
・Using of blockchain as a technology base (Ensuring privacy and interoperability).
・Building a platform in cooperation with the leading blockchain developer, Frog Company.

About the Company

Company Name Quantum Operation Inc.
Representative Kazuma Kato
Establishment October 26, 2017
Capital Stock 100,000,000 JPY (As of June 30, 2020)
Location Y’s Building 2F, 1-2-13 Tsukishima, Chuo-ku, Tokyo
Number of employees 22, including executives and contract workers (As of June 30, 2020)
Directors Akira Ikeda, Masanao Takase, Sumitaka Maruyama, Kenji Kubo, Kazusato Tanida, Hideya Nishimura
Auditor Takeshi Yoshida
Advisors Hironami Kubota (Formerly Nihon Kohden), Kunihide Ichikawa (Formerly Astellas Pharma Inc.), Kenji Sumi (Formerly Astellas Pharma Inc.), Toshiyo Tamura (Next Generation Robotics Laboratory, Waseda University)
Shareholders Taisho Pharmaceutical Co., Alfresa Corporation, Tomita Pharmaceutical Co. and more
Corresponding Banks Sumitomo Mitsui Banking Corporation, Nihonbashi Branch and more
Legal Advisors AZX General Law Office; Uchida & Samejima Law Office
Business Alliances and Business Partners Chiba University of Science, Showa University Hospital, Nomura Medical Devices Co., enstem Inc., The Frog Company, Inc., Okoshiyasu Kyoto AC, Meias Corporation, Xunlong Software (Shenzhen and Dongguan, China) and more

History of the Company

October 2017 Established
October 2017 Business partnership with Xunlong Software (Shenzhen and Dongguan, China)
November 2017 Began the vital data acquisition IoT sensor business.
August 2018 First prototype of the first IoT sensor for acquiring vital data completed.
January 2019 Kunihide Ichikawa was appointed as an advisor.
March 2019 Have commenced third-party allotment of shares through equity crowdfunding.
March 2019 Business partnership with Frog Company, Inc.
July 2019 Business partnership with Tomita Pharmaceutical Co.
November 2019 Business partnership with Taisho Pharmaceutical Co.
January 2020 Business partnership with Alfresa Corporation.
January 2020 Hiro Kubota appointed as an advisor.
February 2020 Start of joint research with Chiba University of Science.
May 2020 Formed a business alliance with Nomura Medical Devices Co.
May 2020 Business alliance with Meias Co.
June 2020 Business partnership with enstem, Inc.
June 2020 Toshiyo Tamura appointed as an advisor.
June 2020 Business partnership with Okoshiyasu Kyoto AC.
June 2020 Pre-release of the Heat Stroke Prediction System.

How did the representative start the company?

(1) My experience in my hometown, Yubari City, Hokkaido, was the trigger.

In 2007, Yubari City’s finances collapsed.
My father retired from Yubari City Hall under the early retirement program. I started my business in Yubari City in 2016 with a U-turn. That’s where I felt the collapse of healthcare.
The maximum number of beds at the hospital in Yubari was 171, but with the financial collapse, the number of beds was reduced to 19.
It’s a 40-minute drive to the next town, and acute patients will not be able to make it in time.
This was the reality.
Then I thought, why not use the IoT to prevent people from getting sick or becoming seriously ill? I was convinced that making this happen would save the world in the future.

(2) My experience with congenital renal artery stenosis.

When I was in junior high school, my blood pressure was found to be abnormal with my highest blood pressure over 180 and lowest blood pressure over 100.
Initially, the cause was unknown and my arm was tightened every day with cuff blood pressure morning, noon and night.
It was a very painful experience, both physically and mentally, as it affected my life.
In addition to the pain in my arm when the cuff is tightened, I asked myself that was I eating poorly? Is it a genetic abnormality? And it was really painful to see faces of my parents as they apologised to me.
If we could at least make the measurements easier, it would alleviate the physical and mental strain! If blood pressure had been controlled by constant measurement, the range of action would have been increased. This was the event where I felt that constant blood pressure control in people with high blood pressure could save lives.

Profile of the Main Members

Kazuma Kato

Invited as a teacher to join the Transdisciplinary Program for Biomedical Entrepreneurship and Innovation of Osaka University Graduate School of Medicine.
Engaged in the PM of a major mission-critical system at Intec, Inc.
Later, he was co-chair of the Japan School of Policy Making.

He served as CIO of Green Ship, Inc.
He is also a director of the NPO Yubari Tourism Association and a member of the Yubari Chamber of Commerce and Industry.

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